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Basic Study
Transforming Growth Factor-β Induces Interleukin-6 Secretion from Human Ligamentum Flavum–Derived Cells through Partial Activation of p38 and p44/42 Mitogen-Activated Protein Kinases
Yuta Goto, Kenji Kato, Kiyoshi Yagi, Yohei Kawaguchi, Hiroki Yonezu, Tomoko Koshimae, Yuko Waguri-Nagaya, Hideki Murakami, Nobuyuki Suzuki
Asian Spine J. 2023;17(6):997-1003.   Published online November 10, 2023
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Clinical Study
Improvements in Intractable Lumbar and LowerExtremity Symptoms after Systemic Administration of Tocilizumab, an Anti-interleukin-6 Receptor Antibody
Takeshi Sainoh, Sumihisa Orita, Masayuki Miyagi, Miyako Suzuki-Narita, Yoshihiro Sakuma, Yasuhiro Oikawa, Go Kubota, Jun Sato, Yasuhiro Shiga, Kazuki Fujimoto, Yawara Eguchi, Masao Koda, Yasuchika Aoki, Tsutomu Akazawa, Takeo Furuya, Junichi Nakamura, Hiroshi Takahashi, Satoshi Maki, Masahiro Inoue, Hideyuki Kinoshita, Masaki Norimoto, Takashi Sato, Masashi Sato, Masahiro Suzuki, Keigo Enomoto, Hiromitsu Takaoka, Norichika Mizuki, Takashi Hozumi, Ryuto Tsuchiya, Geundong Kim, Takuma Otagiri, Tomohito Mukaihata, Takahisa Hishiya, Seiji Ohtori, Kazuhide Inage
Asian Spine J. 2022;16(1):99-106.   Published online May 21, 2021
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Basic Study
p38 Mitogen-Activated Protein Kinase Is Involved in Interleukin-6 Secretion from Human Ligamentum Flavum–Derived Cells Stimulated by Tumor Necrosis Factor-α
Kiyoshi Yagi, Yuta Goto, Kenji Kato, Nobuyuki Suzuki, Akira Kondo, Yuya Waseda, Jun Mizutani, Yohei Kawaguchi, Yuji Joyo, Yuko Waguri-Nagaya, Hideki Murakami
Asian Spine J. 2021;15(6):713-720.   Published online December 28, 2020
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Angiopoietin-Like Protein 2 Induces Synovial Inflammation in the Facet Joint Leading to Degenerative Changes via Interleukin-6 Secretion
Kazuki Sugimoto, Takayuki Nakamura, Takuya Tokunaga, Yusuke Uehara, Tatsuya Okada, Takuya Taniwaki, Toru Fujimoto, Yuichi Oike, Eiichi Nakamura
Asian Spine J. 2019;13(3):368-376.   Published online January 29, 2019
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