1. Kang DG, Holekamp TF, Wagner SC, Lehman RA Jr. Intrasite vancomycin powder for the prevention of surgical site infection in spine surgery: a systematic literature review. Spine J 2015;15:762–770. PMID:
25637469.
2. Bakhsheshian J, Dahdaleh NS, Lam SK, Savage JW, Smith ZA. The use of vancomycin powder in modern spine surgery: systematic review and meta-analysis of the clinical evidence. World Neurosurg 2015;83:816–823. PMID:
25535069.
3. Xiong L, Pan Q, Jin G, Xu Y, Hirche C. Topical intrawound application of vancomycin powder in addition to intravenous administration of antibiotics: a meta-analysis on the deep infection after spinal surgeries. Orthop Traumatol Surg Res 2014;100:785–789. PMID:
25281550.
4. Khan NR, Thompson CJ, DeCuypere M, et al. A meta-analysis of spinal surgical site infection and vancomycin powder. J Neurosurg Spine 2014;21:974–983. PMID:
25259555.
5. Evaniew N, Khan M, Drew B, Peterson D, Bhandari M, Ghert M. Intrawound vancomycin to prevent infections after spine surgery: a systematic review and meta-analysis. Eur Spine J 2015;24:533–542. PMID:
24838506.
6. Alcala-Cerra G, Paternina-Caicedo AJ, Moscote-Salazar LR, Gutierrez-Paternina JJ, Nino-Hernandez LM. Application of vancomycin powder into the wound during spine surgery: systematic review and meta-analysis. Rev Esp Cir Ortop Traumatol 2014;58:182–191. PMID:
24703108.
7. Glotzbecker MP, Riedel MD, Vitale MG, et al. What's the evidence?: systematic literature review of risk factors and preventive strategies for surgical site infection following pediatric spine surgery. J Pediatr Orthop 2013;33:479–487. PMID:
23752143.
8. Zebala LP, Chuntarapas T, Kelly MP, Talcott M, Greco S, Riew KD. Intrawound vancomycin powder eradicates surgical wound contamination: an in vivo rabbit study. J Bone Joint Surg Am 2014;96:46–51. PMID:
24382724.
9. Philp AM, Raja S, Philp A, Ede MP, Jones SW. The effect of vancomycin and gentamicin antibiotics on human osteoblast proliferation, metabolic function and bone mineralisation. Spine (Phila Pa 1976) 2016 5 24 PMID:
10.1097/BRS.0000000000001712. [Epub].
10. Goldschmidt E, Rasmussen J, Chabot JD, et al. The effect of vancomycin powder on human dural fibroblast culture and its implications for dural repair during spine surgery. J Neurosurg Spine 2016;25:665–670. PMID:
27258478.
11. Mendoza MC, Sonn KA, Kannan AS, et al. The effect of vancomycin powder on bone healing in a rat spinal rhBMP-2 model. J Neurosurg Spine 2016;25:147–153. PMID:
27035510.
12. Ghobrial GM, Cadotte DW, Williams K Jr, Fehlings MG, Harrop JS. Complications from the use of intrawound vancomycin in lumbar spinal surgery: a systematic review. Neurosurg Focus 2015;39:E11.
13. Eder C, Schenk S, Trifinopoulos J, et al. Does intrawound application of vancomycin influence bone healing in spinal surgery? Eur Spine J 2016;25:1021–1028. PMID:
25904413.
14. Martin JR, Adogwa O, Brown CR, et al. Experience with intrawound vancomycin powder for spinal deformity surgery. Spine (Phila Pa 1976) 2014;39:177–184. PMID:
24158179.
15. Gaviola ML, McMillian WD, Ames SE, Endicott JA, Alston WK. A retrospective study on the protective effects of topical vancomycin in patients undergoing multilevel spinal fusion. Pharmacotherapy 2016;36:19–25. PMID:
26749522.
16. Lee GI, Bak KH, Chun HJ, Choi KS. Effect of using local intrawound vancomycin powder in addition to intravenous antibiotics in posterior lumbar surgery: midterm result in a single-center study. Korean J Spine 2016;13:47–52. PMID:
27437012.
17. Dennis HH, Wei DT, Darren KZ, et al. Is intraoperative local vancomycin powder the answer to surgical site infections in spine surgery? Spine (Phila Pa 1976) 2016 5 23 PMID:
10.1097/BRS.0000000000001710. [Epub].
18. Martin JR, Adogwa O, Brown CR, et al. Experience with intrawound vancomycin powder for posterior cervical fusion surgery. J Neurosurg Spine 2015;22:26–33. PMID:
25380539.
19. Suh BK, Moon SH, Kim TH, et al. Efficacy of antibiotics sprayed into surgical site for prevention of the contamination in the spinal surgery. Asian Spine J 2015;9:517–521. PMID:
26240708.
20. Theologis AA, Demirkiran G, Callahan M, Pekmezci M, Ames C, Deviren V. Local intrawound vancomycin powder decreases the risk of surgical site infections in complex adult deformity reconstruction: a cost analysis. Spine (Phila Pa 1976) 2014;39:1875–1880. PMID:
25077909.
21. Strom RG, Pacione D, Kalhorn SP, Frempong-Boadu AK. Decreased risk of wound infection after posterior cervical fusion with routine local application of vancomycin powder. Spine (Phila Pa 1976) 2013;38:991–994. PMID:
23324930.
22. Sweet FA, Roh M, Sliva C. Intrawound application of vancomycin for prophylaxis in instrumented thoracolumbar fusions: efficacy, drug levels, and patient outcomes. Spine (Phila Pa 1976) 2011;36:2084–2088. PMID:
21304438.
23. Tubaki VR, Rajasekaran S, Shetty AP. Effects of using intravenous antibiotic only versus local intrawound vancomycin antibiotic powder application in addition to intravenous antibiotics on postoperative infection in spine surgery in 907 patients. Spine (Phila Pa 1976) 2013;38:2149–2155. PMID:
24048091.
24. Mariappan R, Manninen P, Massicotte EM, Bhatia A. Circulatory collapse after topical application of vancomycin powder during spine surgery. J Neurosurg Spine 2013;19:381–383. PMID:
23829290.
25. Ghobrial GM, Thakkar V, Andrews E, et al. Intraoperative vancomycin use in spinal surgery: single institution experience and microbial trends. Spine (Phila Pa 1976) 2014;39:550–555. PMID:
24480966.
26. Tennent DJ, Shiels SM, Sanchez CJ Jr, et al. Time-dependent effectiveness of locally applied vancomycin powder in a contaminated traumatic orthopaedic wound model. J Orthop Trauma 2016;30:531–537. PMID:
27124826.